Source:

 

Liang, Y., Diehn, M., Watson, N., Bollen, A. W., Aldape, K. D., Nicholas, M. K., ... & Israel, M. A. (2005). Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proceedings of the National Academy of Sciences of the United States of America, 102(16), 5814-5819.

 

Original data:

 

http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE4058

 

Description:

 

Glioblastoma multiforme (GBM) is the most common form of malignant glioma, characterized by genetic instability, intratumoral histopathological variability, and unpredictable clinical behavior. The authors investigated global gene expression in surgical samples of brain tumors. Gene expression profiling revealed large differences between normal brain samples and tumor tissues and between GBMs and lower-grade oligodendroglial (ODG) tumors.

 

Sample distribution:

 

  • Liang: 28 GBM, 6 ODG and 3 Normal.